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KMID : 1134820210500080832
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Journal of the Korean Society of Food Science and Nutrition
2021 Volume.50 No. 8 p.832 ~ p.842
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Estimation of Measurement Uncertainty of Dioxin (2,3,7,8-Tetrachlorodibenzo-p-dioxin) Analysis in Food
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Park Chan-Jong
Kim Han-Sol
Ahn Tae-Hyun
Chong Eun-A
Lee Ji-Eun
Seo Su-Jin
Koo Yong-Eui
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Abstract
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In this study, the quality assurance system was established in line with international standards by acquiring ISO/IEC 17025 accreditation for dioxin analysis in food. In order to strengthen the reliability and public credibility of the results, ISO/IEC 17025 recommends to provide information on ‘measurement uncertainty’ along with the measured values. Based on the ‘Guide to the Estimation of Uncertainty in Measurement’ (GUM) and the ‘EURACHEM/CITAC guide’, a model relational equation for estimating the uncertainty of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8- TCDD) analysis in food was established. In the process of analyzing the 2,3,7,8-TCDD concentration in food, the measurement uncertainty was calculated by considering the important uncertainty factors that may exist. The combined uncertainty was calculated by using the eight uncertainty factors (precision, recovery, calibration curve, repeat measurement of sample, standard, internal standard, volume of sample, and weight of sample). The biggest factor influencing the uncertainty was the recovery. In the 95% confidence interval, the expanded uncertainty was calculated as 3.8 pg/g using k-value (2). The final expression can be stated as 12.0±3.8 pg/g (confidence interval 95%, k=2). Through the measurement uncertainty estimation, the factors that cause analysis errors during the analytical procedure of dioxin were identified and the degree of their influence on the results was calculated. The reliability of the analysis result was obtained by calculating the uncertainty, which is the basic element of ISO/IEC 17025 and minimizing the uncertainty factors.
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KEYWORD
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dioxin, ISO/IEC 17025, measurement uncertainty, quality assurance, standardization
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